Description
Human BTN2A1 / Butyrophilin Protein, His Tag (MALS verified) | BT1-H52H6-1mg| Gentaur Distribution US, UK & Europe
Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.
Source: Human BTN2A1/Butyrophilin, His Tag (BT1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 29 - Ala 248 (Accession # Q7KYR7-2).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gln 29 - Ala 248.
Conjugate: Unconjugated.
Molecular Weight: 26.4 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.4 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
