Description
Human BTN1A1 / Butyrophilin Protein, Fc Tag | BT1-H5253-1mg| Gentaur Distribution US, UK & Europe
Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Source: Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 242 (Accession # AAH96312).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Ala 27 - Arg 242.
Conjugate: Unconjugated.
Molecular Weight: 50.6 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
