Description
Human Beta-NGF Protein, premium grade | BEF-H5214-50ug| Gentaur Distribution US, UK & Europe
Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.
Source: Human Beta-NGF Protein, premium grade (BEF-H5214) is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Ala 241 (Accession # P01138).
Format: Powder.
Tag: Native.
Expression System: HEK293.
Expression Region: Ser 122 - Ala 241.
Conjugate: Unconjugated.
Molecular Weight: 13.5 kDa.
Characteristics: This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as 14-15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 20 mM NaAC, 150 mM NaCl, pH5.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
