Description
Human Bcl-x / BCL2L1 Protein, His Tag | BC1-H5120-1mg| Gentaur Distribution US, UK & Europe
Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Source: Human Bcl-x, His Tag (BC1-H5120) is expressed from E.coli cells. It contains AA Met 1 - Arg 212 (Accession # AAH19307).
Format: Powder.
Tag: C-6×His.
Expression System: E. coli.
Expression Region: Met 1 - Arg 212.
Conjugate: Unconjugated.
Molecular Weight: 24.6 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.6 kDa. The protein migrates as 25-27 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 20 mM HEPES, 50 mM KCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
