Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag | AN4-H5243-1mg

Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein, His Tag | AN4-H5243-1mg| Gentaur Distribution US, UK & Europe

Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer, and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.

Source: Human Angiopoietin-like 4 (166-406), His Tag (AN4-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 166 - Ser 406 (Accession # Q9BY76-1).

Format: Powder.

Tag: N-6×His.

Expression System: HEK293.

Expression Region: Pro 166 - Ser 406.

Conjugate: Unconjugated.

Molecular Weight: 27.9 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 31-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM MOPS, 100 mM NaCl, pH7.2.

Storage Conditions: -20℃.

Shipping Conditions: RT