Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag | EM2-H5142-100ug

Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag | EM2-H5142-100ug| Gentaur Distribution US, UK & Europe

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.

Source: Human AIMP1, His Tag (EM2-H5142) is expressed from E. coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1).

Format: Powder.

Tag: N-6×His.

Expression System: E. coli.

Expression Region: Ala 2 - Lys 312.

Conjugate: Unconjugated.

Molecular Weight: 35.2 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE).

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT