Description
Human 2B4 / CD244 / SLAMF4 Protein, His Tag | 2B4-H5224-100ug| Gentaur Distribution US, UK & Europe
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
Source: Human 2B4, His Tag (2B4-H5224) is expressed from human 293 cells (HEK293) . It contains AA Cys 22 - Arg 221 (Accession # Q9BZW8-2).
Format: Powder.
Tag: C-6×His.
Expression System: HEK293.
Expression Region: Cys 22 - Arg 221.
Conjugate: Unconjugated.
Molecular Weight: 23.1 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.1 kDa. The protein migrates as 35-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation..
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
