Description
HSP90 Antibody | F52639-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 803CT9.1.2
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Buffer: N/A
Limitation: This HSP90 antibody is available for research use only.
Purity: Purified
Description: Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]
Immunogen: A portion of amino acids from 150-400 of the human protein were used as the immunogen for this HSP90 antibody.
Storage: Aliquot the HSP90 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.