Description
HSP70 Antibody / HSPA1A / HSPA1B | F54222-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This HSP70 antibody is available for research use only.
Purity: Antigen affinity purified
Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Immunogen: An amino acid sequence surrounding Y41 of human HSPA1A/B was used as the immunogen for the HSP70 antibody.
Storage: Aliquot the HSP70 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
