Description
HSP27 Antibody / HSPB1 | V9277-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: HSPB1/6490R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: WB, IHC-P
Application Details: Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the recombinant HSP27 antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: HSP27, also referred to as Heat shock protein beta-1 (HSPB1), Estrogen-Regulated 24K protein, and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.
Immunogen: Recombinant human full-length HSP27 protein was used as the immunogen for the recombinant HSP27 antibody.
Storage: Aliquot the recombinant HSP27 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Predominantly cytoplasmic with some nuclear
