HSP27 Antibody / HSPB1 | V2134SAF-100UG

HSP27 Antibody / HSPB1 | V2134SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: G3.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This HSP27 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). HSP27 was recently found to be identical to the estrogen-induced 'p29' and '24K' protein. About 50% of breast carcinomas are positive for HSP27, especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.

Immunogen: Partially purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells was used as the immunogen for this antibody.

Storage: Store the HSP27 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).