Description
HSP10 Antibody | R30887 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P, ICC, IF, FACS
Buffer: N/A
Limitation: This HSP10 antibody is available for research use only.
Purity: Antigen affinity
Description: Heat shock 10kDa protein 1, also called CPN10, GROES, and HSP10, is a protein that in humans is encoded by the HSPE1 gene. It is a heptameric ring of identical 10.4-kD subunits that binds to each end of GroEL to form a symmetric, functional heterodimer. The transcriptional activity of the promoter fragment in the HSP60 direction is approximately twice that in the HSP10 direction under normal growth conditions; upon heat shock, promoter activity in either direction increased by a factor of approximately 12. Mutational drifts performed in vitro with 4 different enzymes indicated the HSP10 overexpression doubled the number of accumulating mutations, and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with higher destabilizing effects.
Immunogen: An amino acid sequence from the C-terminus of human Heat shock protein 10 (VVLDDKDYFLFRDGDILGKYVD) was used as the immunogen for this HSP10 antibody.
Storage: After reconstitution, the HSP10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
