HPK1 Assay Kit | 79775

HPK1 Assay Kit | 79775 | Gentaur US, UK & Europe Disrtribition

Category: Kinase/Assay Kit

Application: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: HPK1 (MAP4K1) or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. It is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. HPK1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76, suggesting HPK1 could be a novel target for anti-tumor immunotherapy.

Description: The HPK1 Assay Kit is designed to measure HPK1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

Product Type: Assay Kit

Shippement Condition: -80°C