Hopx Antibody | F53366-0.08ML

Hopx Antibody | F53366-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Hopx antibody is available for research use only.

Purity: Antigen affinity

Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

Immunogen: This mouse Hopx antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of mouse Hopx.

Storage: Aliquot the Hopx antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.