HLA-DQA1 Antibody | F40097-0.08ML

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SKU:
800-F40097-0.08ML
Weight:
1.20 KGS
€644.00
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Description

HLA-DQA1 Antibody | F40097-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This HLA-DQA1 antibody is available for research use only.

Purity: Antigen affinity

Description: HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Immunogen: A portion of amino acids 39-66 from the human protein was used as the immunogen for this HLA-DQA1 antibody.

Storage: Aliquot the HLA-DQA1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

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Additional Information

Size:
0.08 mL
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