Description
Histone H4 Antibody (Methyl-Lys20 specific) | F48612-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, FACS, WB, DB, ELISA
Buffer: N/A
Limitation: This H4 antibody is available for research use only.
Purity: Antigen affinity
Description: Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.
Immunogen: Amino acids surrounding the K20 methylation site of the human protein were used as the immunogen for this Histone H4 antibody.
Storage: Aliquot the H4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
