HIF1A Antibody (HIF-1 alpha) | F50745-0.08ML

HIF1A Antibody (HIF-1 alpha) | F50745-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC, IF, FACS, ELISA

Buffer: N/A

Limitation: This HIF1A antibody is available for research use only.

Purity: Purified

Description: HIF1A functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. [UniProt]

Immunogen: A portion of amino acids 519-547 from the human protein was used as the immunogen for this HIF1A antibody.

Storage: Aliquot the HIF1A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.