HIF1A Antibody (HIF-1 alpha) | F47799-0.08ML

HIF1A Antibody (HIF-1 alpha) | F47799-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This HIF1A antibody is available for research use only.

Purity: Antigen affinity

Description: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Immunogen: A portion of amino acids 735-762 from the human protein was used as the immunogen for this HIF1A antibody.

Storage: Aliquot the HIF1A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.