Description
HIF1A Antibody | F50745-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, IF, FACS, ELISA
Buffer: N/A
Limitation: This HIF1A antibody is available for research use only.
Purity: Purified
Description: HIF1A functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. [UniProt]
Immunogen: A portion of amino acids 519-547 from the human protein was used as the immunogen for this HIF1A antibody.
Storage: Aliquot the HIF1A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
