HIF-3 alpha Antibody | R31264

HIF-3 alpha Antibody | R31264 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Rat

Application: WB

Buffer: N/A

Limitation: This HIF-3 alpha antibody is available for research use only.

Purity: Antigen affinity

Description: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. This gene involved in adaptive response to hypoxia. HIF3a suppresses hypoxia-inducible expression of HIF1a and HIF2a. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3a-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

Immunogen: An amino acid sequence from the C-terminus of human HIF3A (DDDFQLNASEQLPRAYHR) was used as the immunogen for this HIF-3 alpha antibody.

Storage: After reconstitution, the HIF-3 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.