Description
HFE Antibody (Hereditary hemochromatosis protein) | R32770 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Limitation: This HFE antibody is available for research use only.
Purity: Antigen affinity
Description: Human hemochromatosis protein, also known as HFE, is a protein which in humans is encoded by the HFE gene. The gene is located on short arm of chromosome 6 at location 6p21.3. It is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.
Immunogen: Amino acids Q82-R199 from the human protein were used as the immunogen for the HFE antibody.
Storage: After reconstitution, the HFE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
