Hes1 Antibody | F53006-0.08ML

Hes1 Antibody | F53006-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This Hes1 antibody is available for research use only.

Purity: Antigen affinity

Description: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

Immunogen: This mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 205-239 amino acids from the C-terminal region of mouse Hes1.

Storage: Aliquot the Hes1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.