Description
HER3 Antibody (ERBB3) | F50603-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, FACS, ELISA
Buffer: N/A
Limitation: This HER3 antibody is available for research use only.
Purity: Purified
Description: HER3/ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins and NTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This protein is predominantly expressed in epithelial tissues and brain. The cytoplasmic part of the receptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote its association with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressed in a subset of human mammary tumors.
Immunogen: A portion of amino acids 24-55 from the human protein was used as the immunogen for this HER3 antibody.
Storage: Aliquot the HER3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
