Description
HER2 Antibody / ErbB2 / Extracellular region | V9132-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: ERBB2/4376R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: FACS, IF, IHC-P
Application Details: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the recombinant ErbB2 antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Immunogen: Recombinant extracellular domain of human c-erbB2/HER2 was used as the immunogen for the recombinant ErbB2 antibody.
Storage: Aliquot the recombinant ErbB2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Cell Surface
