HER2 Antibody / ErbB2 / C-terminal region | F54939-0.4ML

HER2 Antibody / ErbB2 / C-terminal region | F54939-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, WB

Buffer: N/A

Limitation: This ErbB2 antibody is available for research use only.

Purity: Purified

Description: ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.

Immunogen: A portion of amino acids 1206-1236 from the human protein was used as the immunogen for the ErbB2 antibody.

Storage: Aliquot the ErbB2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.