Description
Hepatocyte Specific Antigen Antibody | V3109IHC-7ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Format: Purified
Clone: HepPar1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This HepPar-1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Hepatocyte Paraffin 1 or HepPar-1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Immunogen: Extract of a formalin-fixed, rejected-allograft of a human liver was used as the immunogen for the HepPar1 antibody.
Storage: Store the HepPar1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
