Description
HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line | CHEK-ATP132-2Vials| Gentaur Distribution US, UK & Europe
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Species: Human.
Molecule: FcRn (FCGRT & B2M) .
Tag: C-GFP | Native.
Format: Liquid.
Application: Human FcRn (FCGRT&B2M), GFP Tag-HEK293 cells stably expressing exogenous FCGRT ( AA sequence: Ala 24 - Ala 365, Protein Acc.#: P55899-1 ) & B2M ( AA sequence: Ile 21 - Met 119, Protein Acc.#: P61769-1 ) . At the same time, GFP protein as a marker was expressed in HEK293/FcRn (FCGRT & B2M), GFP Tag Cells for screening positive cells by FACS.
Storage Conditions: Frozen in liquid nitrogen.
Shipping Conditions: Dry ice
