HDAC4 Polyclonal Antibody | E-AB-31646

HDAC4 Polyclonal Antibody | E-AB-31646 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, ELISA

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of Ser632.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:20000

Conjugation: Unconjugated

Calculated Molecular Weight: 119 kDa

Observed Molecular Weight: 119 kDa

Clonality: Polyclonal