Description
HDAC4 Antibody | F43191-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IF, WB, IHC, ELISA
Buffer: N/A
Limitation: This HDAC4 antibody is available for research use only.
Purity: Antigen affinity
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Immunogen: A portion of amino acids 1049-1077 from the human protein was used as the immunogen for this HDAC4 antibody.
Storage: Aliquot the HDAC4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
