Description
HCoV-OC43 Nucleocapsid protein, His Tag | NUN-V5145-1mg| Gentaur Distribution US, UK & Europe
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Source: HCoV-OC43 Nucleocapsid, His Tag (NUN-V5145) is expressed from E. coli cells. It contains AA Met 1 - Ile 448 (Accession # P33469-1).
Format: Powder.
Tag: N-6×His.
Expression System: E. coli.
Expression Region: Met 1 - Ile 448.
Conjugate: Unconjugated.
Molecular Weight: 50.3 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).
Purity: 90%.
Buffer: 40 mM PB, 500 mM NaCl, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
