HCoV-OC43 Nucleocapsid protein, His Tag | NUN-V5145-100ug

HCoV-OC43 Nucleocapsid protein, His Tag | NUN-V5145-100ug| Gentaur Distribution US, UK & Europe

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Source: HCoV-OC43 Nucleocapsid, His Tag (NUN-V5145) is expressed from E. coli cells. It contains AA Met 1 - Ile 448 (Accession # P33469-1).

Format: Powder.

Tag: N-6×His.

Expression System: E. coli.

Expression Region: Met 1 - Ile 448.

Conjugate: Unconjugated.

Molecular Weight: 50.3 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).

Purity: 90%.

Buffer: 40 mM PB, 500 mM NaCl, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT