HCG-beta Antibody Cocktail | V3154IHC-7ML

HCG-beta Antibody Cocktail | V3154IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: HCGb/54 + HCGb/459

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This HCG-beta antibody cocktail is available for research use only.

Purity: Protein G affinity chromatography

Description: This mAb reacts with a protein of 22kDa, identified as the beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG mAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Immunogen: Recombinant hCG beta protein was used as the immunogens for this hCG beta antibody cocktail.

Storage: Store the HCG-beta antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).