H-Cadherin Antibody / CDH13 | RQ6248

H-Cadherin Antibody / CDH13 | RQ6248 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Rat

Application: WB, IHC-P, IF, FACS, Direct ELISA

Buffer: N/A

Limitation: This Cadherin 13 antibody is available for research use only.

Purity: Affinity purified

Description: H-cadherin (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: A human recombinant partial protein (amino acids E149-A692) was used as the immunogen for the Cadherin 13 antibody.

Storage: After reconstitution, the Cadherin 13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.