GRP94 Antibody / HSP90B1 | V2909IHC-7ML

GRP94 Antibody / HSP90B1 | V2909IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: SPM249

Host Animal: Rat

Clonality: Monoclonal (rat origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This gp96 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Gp96 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This mAb is highly specific and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Gp96 has been briefly studied as a prognostic factor in breast cancer.

Immunogen: Purified glucose regulated protein 94 from chicken oviducts was used as the immunogen for the gp96 antibody.

Storage: Store the gp96 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).