Description
GRB10 Antibody | RQ6357 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Purified
Clone: 5H7
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Monkey, Rat
Application: WB, FACS
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This GRB10 antibody is available for research use only.
Purity: Antigen affinity purified
Description: GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors(e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen: Recombinant human protein (amino acids M1-K251) was used as the immunogen for the GRB10 antibody.
Storage: After reconstitution, the GRB10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
