Granzyme B Antibody | V7638-100UG

Granzyme B Antibody | V7638-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: GZB-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This Granzyme B antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]

Immunogen: Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.

Storage: Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).