Description
Granzyme B Antibody | V7638-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: GZB-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This Granzyme B antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
Immunogen: Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
Storage: Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
