GPNMB Antibody | F45454-0.08ML

GPNMB Antibody | F45454-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This GPNMB antibody is available for research use only.

Purity: Antigen affinity

Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: A portion of amino acids 541-569 from the human protein was used as the immunogen for this GPNMB antibody.

Storage: Aliquot the GPNMB antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.