Description
GPC3 - CHO-K1 Recombinant Cell Line | 78100 | Gentaur US, UK & Europe Disrtribition
Category: Cell Signaling/Cell Line
Application: 1. Useful for screening and validating antibodies against GPC3 and anti-GPC3 CAR-T for immunotherapy research and drug discovery.
2. Useful for GPC3 binding assays to screen for GPC3 ligands.
Background: GPC3, also known as Glypican-3 and OCI5, belongs to the glypican family and is highly expressed in the lungs, liver and kidneys. Its function is tissue dependent and can either promote or suppress tumorigenesis. Being a heparin sulfate proteoglycan, it is overexpressed in neoplasms including malignant melanoma, hepatocellular carcinoma, and testicular yolk sac tumors and plays a significant role in cell growth and differentiation.
Description: Recombinant CHO-K1 cells expressing GPC3 (Glypican 3), a cell surface proteoglycan bearing heparin-sulfate; ref. seq. NM_004484.2.
Product Type: Cell Line
Shippement Condition: -80°C
