Description
GLUT1 Antibody / SLC2A1 | V3920-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: GLUT1/2476
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This GLUT1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a protein of 45-55kDa, which is identified as GLUT1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut1 to Glut12. Glut1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut1 is expressed at variable levels in many human tissues. Overexpression has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).
Immunogen: A portion of amino acids 203-305 from the human protein was used as the immunogen for this GLUT1 antibody.
Storage: Store the GLUT1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).