Description
GITR/TNFRSF18 Polyclonal Antibody | E-AB-66508 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: N/A
Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human GITR/TNFRSF18 (NP_683699.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: WB 1:500-1:2000
Conjugation: Unconjugated
Calculated Molecular Weight: 25 kDa/26 kDa
Observed Molecular Weight: 30 kDa
Clonality: N/A
