Description
GITR Antibody / TNFRSF18 | V8185-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: GITR/1585
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA
Buffer: N/A
Limitation: This TNFRSF18 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.
Immunogen: Human full-length TNFRSF18 protein was used as the immunogen for this TNFRSF18 antibody.
Storage: Store the TNFRSF18 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).