Description
GFRAL Antibody | F54320-0.2ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P, FACS
Buffer: N/A
Limitation: This GFRAL antibody is available for research use only.
Purity: Antigen affinity purified
Description: Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt]
Immunogen: A portion of amino acids 366-394 from the human protein was used as the immunogen for the GFRAL antibody.
Storage: Aliquot the GFRAL antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.