Description
GFP/Firefly Luciferase MM.1S Cell Line | 78376 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: • Use as a control for killing assays • Suitable as a B-cell target for CAR-T or CAR-NK cells for optimizing CAR design
Background: MM.1S are multiple myeloma human B lymphoblasts. The parent cell line MM.1 was established from the peripheral blood of a multiple myeloma patient who had become resistant to steroid-based therapy. MM.1S cells are sensitive to dexamethasone. The cells were infected with an integrating Firefly luciferase-eGFP lentivirus (BPS Bioscience #79980-G) and cloned by limited dilution to get a monoclonal population. The cells stably express both the Firefly luciferase and enhanced GFP genes, making these cells an excellent tool to measure specific killing by CAR-T or NK cells.
Description: Recombinant stable MM.1S cell line constitutively expressing a firefly luciferase and enhanced GFP (eGFP) cassette driven by a CMV promoter.
Product Type: Cell Line
Shippement Condition: -80°C
