Description
GCLC Antibody | F41799-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, IF, FACS, ELISA
Buffer: N/A
Limitation: This GCLC antibody is available for research use only.
Purity: Antigen affinity
Description: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this GCLC antibody.
Storage: Aliquot the GCLC antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
