Description
GBA Polyclonal Antibody | E-AB-19899 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Metabolism, Neuroscience, Signal transduction
Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Lead Time: 7~10 days
Concentration: 1.56 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human GBA
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 60 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal