Description
GATA4 Antibody | F43474-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This GATA4 antibody is available for research use only.
Purity: Purified
Description: GATA4 is a transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. [UniProt]
Immunogen: A portion of amino acids 298-328 from the human protein was used as the immunogen for this GATA4 antibody.
Storage: Aliquot the GATA4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.