Description
GAK Antibody | F40086-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This GAK antibody is available for research use only.
Purity: Purified
Description: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.
Immunogen: A portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody.
Storage: Aliquot the GAK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
