GAK Antibody | F40086-0.08ML

GAK Antibody | F40086-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This GAK antibody is available for research use only.

Purity: Purified

Description: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.

Immunogen: A portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody.

Storage: Aliquot the GAK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.