Description
GAD65 Antibody / GAD2 | F54577-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P, IF
Buffer: N/A
Limitation: This GAD2 antibody is available for research use only.
Purity: Antigen affinity purified
Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Immunogen: A portion of amino acids 109-138 from the human protein was used as the immunogen for the GAD2 antibody.
Storage: Aliquot the GAD2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
