GAD65 Antibody / GAD2 | F54577-0.4ML

GAD65 Antibody / GAD2 | F54577-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC-P, IF

Buffer: N/A

Limitation: This GAD2 antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Immunogen: A portion of amino acids 109-138 from the human protein was used as the immunogen for the GAD2 antibody.

Storage: Aliquot the GAD2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.