FTL Antibody / Ferritin Light Chain | V8527-20UG

FTL Antibody / Ferritin Light Chain | V8527-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: FTL/3872R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: WB, IHC-P

Application Details: Western blot: 2-4ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Application Note: Optimal dilution of the recombinant Ferritin Light Chain antibody should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Immunogen: Recombinant full-length human FTL protein was used as the immunogen for the recombinant Ferritin Light Chain antibody.

Storage: Store the recombinant Ferritin Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cytoplasmic